First Study
The first double-blind research study of Irvingia Gabonensis (African Mango extract) in humans took place in 2005, comparing participants taking Irvingia Gabonesis to a control group on a placebo. All subjects maintained their normal calorie intake.
After 30 days, the participants taking African Mango extract lost an average of 12.3 pounds. On average, subjects taking Irvingia Gabonensis lost 5.3% of their body weight, while the control group only lost 1.3%, which represents a significant difference in weight loss between the two groups. At the same time, the African Mango extract group also exhibited significant reduction in their waist measurements compared to the control group.
The study was published in the May 2005 issue of the journal Lipids in Health and Disease. Read the details from the U.S. National Library of Medicine, National Institutes of Health: http://www.ncbi.nlm.nih.gov/pubmed/15916709
Second Study
Remarkable results were also found in a second, larger clinical trial of Irvingia Gabonensis (African Mango extract) in 2009. Over a 10-week period, otherwise healthy overweight and obese participants took either Irvingia Gabonesis (150 mg twice daily before meals) or a placebo, while making no other changes to their diet and exercise levels.
By the end of the study, those using African Mango extract had lost a significant amount of weight – an average of 28 pounds – while the placebo group lost virtually no weight (~1.5 pounds). The researchers found that the subjects in the African Mango extract group experienced “significant improvements in body weight, body fat, and waist circumference”. They had a 13.1% decrease in body weight, shed 6.7 inches from their waistline, and reduced their total body fat by 18.4%.
According to the researchers, Irvingia Gabonensis “safely and significantly reduces body weight in overweight and/or obese subjects, and has a favorable impact upon a variety of other metabolic parameters.”
The researchers also noted that cholesterol levels and blood sugar levels improved significantly compared to the control group. These remarkable blood marker changes reveal specific mechanisms responsible for the profound weight-loss effects observed in participants taking Irvingia Gabonensis. These beneficial changes would also provide considerable protection against diabetes and cardiovascular disease beyond the fat loss benefits.
The study was published in the March 2009 issue of the journal Lipids in Health and Disease. Read the details from the U.S. National Library of Medicine, National Institutes of Health: http://www.ncbi.nlm.nih.gov/pubmed/19254366
This landmark study was so significant it made international news, and was reported by Reuters Health on March 23, 2009. Read their full report online titled “Fruit extract shows promise as weight-loss aid”.
The study was also featured on FOX News. Check out their March 29, 2009 news story online titled “Exotic Fruit Extract May Shed Pounds, Lower Cholesterol”.
REFERENCES
1. Faloon, William. “More Weight Loss than Any Other Discovery in Supplement History.” Life Extension Magazine, 2008.
2. Van Heerden, Ingrid. “African Mango – Weight Loss Wonder Fruit?” Health 24 Newsletter, July 11, 2001.
3. Ngondi JL, Oben JE, and Minka SR. “The effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in Cameroon.
” Lipids in Health and Disease. 2005 May 25;4:12.
4. Ngondi JL, Etoundi BC, Nyangono CB, Mbofung CM, and Oben JE. “IGOB131, a novel seed extract of the West African plant Irvingia gabonensis,
significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo
controlled investigation.” Lipids in Health and Disease. 2009 Mar 2;8:7.
5. “Fruit extract shows promise as weight-loss aid.” Reuters Health, March 23 2009.
6. “Exotic Fruit Extract May Shed Pounds, Lower Cholesterol.” FOX News, March 29, 2009.

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